Jan 5, Portal cavernoma (PC) is the most critical condition with risk or variceal hemorrhage in pediatric patients. We retrospectively investigated the. Cavernous transformation of the portal vein (also called portal cavernoma) occurs when the native portal vein is thrombosed and myriads of collateral channels. La obstrucción de la vena porta con un hígado sano es una causa frecuente de hipertensión portal en los niños. El curso natural de la enfermedad se.

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Gut, 40pp. In most of the patients, the liver functions were satisfactory; the high portal vein pressure is the prominent problem to control. The clinical records were thoroughly collected upon admission or referral.

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Up to now, the totally agreed upon guidelines for this disease are unavailable, and therapeutic options vary in different centers; when these fail, further medical options are limited, especially for intrahepatic cavernoma. Univariate and multivariate logistic regression models were used portall examine the independent predictors of recurrent variceal bleeding.

J Clin Gastroenterol, 26pp. We retrospectively czvernomatosis the patients with PC focusing on the predictors for recurrent variceal bleeding. Ten patients were excluded from the study because they lacked proper documentation. Does umbilical vein catheterization to exchange transfusion lead to portal vein thrombosis.

These changes lead to a central liver hypertrophy and peripheral liver atrophy 8. However, in case of orphans, street children etc. Eur J Surg,pp. Thrombosis due to catheterization nkos infants and children. Second, our database does include different therapeutic interventions that patients received. The cavernomatozis of ascites, collateral circulation, and portal venous pressure evaluation are important and could predict the postsurgical recurrent variceal bleeding in patients with portal cavernoma.

Niis and coronal of sixty-four-slice CT angiography indicate a dilated and tortuous portal vein, b intrahepatic PV, and c collateral circulation arrow. These vessels drain variably into the left and right portal veins or more distally into the liver. Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage.

Based on the importance of ascites in pediatric patients with portal cavernoma, therapeutic decision making needs to be altered according to the presence of ascites [ 20 ]. After reading the instructions em on the “Register” button in the Stream 1 block 1 section. Seven cases presented paraumbilical vein patefaction, showing tortuous dilation changes in the ligamentum teres hepatis.


Afterslice computed tomography CT was available in our hospital, so it was performed in the latest 83 cases. In combination with the other markers, it offers a non-invasive predictive profile of great significance for monitoring and surveillance of the porttal with portal cavernoma Palabras clave: We found that the death resulting from sudden and massive variceal bleeding always occurred in the short term after medical intervention of PC, which is in accordance with report by others [ 24 ].

Although all these cavdrnomatosis vessels were conserved during surgery, most of the patients displayed upper gastrointestinal bleeding after surgery. Because the risk of bleeding in these patients can decrease with age, non-aggressive management is preferred whenever possible.

Case 1 Case 1. In our study, two patients who underwent recurrent variceal bleeding died 5 months after surgery. Previous studies have reported that year survival rate in patients is closely associated with advanced age, presence of malignancy and cirrhosis, high bilirubin, and deterioration of liver function [ 7 ].

Ann Intern Med,pp. Under the slice CT measurement, portal cavernoma was visualized with a tortuous network of veins in the hilum.

Because treatment is currently inadequate, it is imperative that a better understanding of the predictors for recurrent variceal bleeding of PC is gained to identify new targets for therapeutic intervention. Age, sex, bleeding, splenic length by ultrasound, platelet count, fibrinogen, prothrombin time and ratio. Indeed, the presence of ascites is caused not only by the portal pressure itself, but also by a deterioration of liver function and a lower level of serum albumin and sodium, which are cavdrnomatosis correlated with the presence of ascites [ 1819 ].

Given the complexity and rarity of the portal cavernoma, a variety of surgical techniques, such as various portosystemic shunts and gastrosplenic decompression, have been proposed to focus on the prevention and treatment of variceal hemorrhage, prevention of recurrent thrombosis, and treatment of symptomatic portal biliopathy [ 56 ].

The minimum poryal to take admission in the Senior Secondary Course is 15 years. The surgical procedure was considered if patients presented with a long history of repeated gastrointestinal syndromes unresponsive to conservative therapies.

Cavernous transformation of the portal vein CTPV is a sequela of portal vein thrombosis and is the replacement of the normal single channel portal vein with numerous tortuous venous channels. Currently, there is no reference standard for PC intervention, so the inclusion criteria may influence the application of indicators in patients with variceal bleeding. Subject Characteristics This study was performed in accordance with the ethical standards prescribed by the Helsinki Declaration of the World Medical Association and approved by the Institutional Review Board of the Chongqing Medical University and Shandong University.


It is therefore important that gastroenterologists become aware of the fact that, in long-term survivors who have undergone the variceal hemorrhage operation, complications such as recurrent variceal hemorrhage and portal hypertension may occur. During the follow-up period, 24 patients exhibited onset of recurrent variceal bleeding.

Surgical procedure selection was based on overall consideration of several factors, according to the severity of vascular dilation, the PC location, and the extent of liver dysfunction. Edit article Share article View revision history. Indexed in Science Citation Index Expanded. Coronary venous reflux is an indicator of esophageal variceal rupture, the important pathological symptom of portal hypertension.

Given the descriptive design, which risk factors we found causal cannot be distinguished currently. Typically these changes are:. Ville de Goyet, D.

To our knowledge, this is the largest study to describe prognostic information and the outcome of portal cavernoma patients in pediatrics. The patients with the most severe hematemesis presented with tortuous and stiffness in left gastric veins in slice CT scan.

J Vascular Surg, 30pp.

Trombosis de la vena porta | Anales de Pediatría

Flow is generally hepatopetal and continuous with little if any respiratory or cardiac variation 4. Slow blood flow through this tortuous network of veins, redistribution of the blood, and new thromboses all contribute to the increase of portal vein pressure [ 2 — 4 ]. Noninvasive markers for detection of varicose veins and risk of bleeding have been used in portal hypertension due to cirrhosis of the liver.

Following the splenectomy and gastric fundic and lower esophageal vascular disconnection, no severe hematemesis recurrence or obvious black tarry feces presented in 33 pediatric patients. The portal venous system and portal hypertension.